Opthamet Eye Drops

Antazoline 0.05% + Tetryzoline 0.04% eye prep
0.05% + 0.04%
Drug International Ltd.
Pack size 10 ml drop
Dispensing mode
Source
Agent
Retail Price 110.35 AED

Indications

Opthamet Eye Drops is used for: Conjunctivitis, Keratitis, Inflammatory eye conditions, Hay-fever

Adult Dose

Adult: Ophth: Apply 1-2 drops 2-3 times/day for up to 14 days. Ophth Conjunctival decongestant Instill 1-2 drops up to 4 times/day for 3-4 days unless directed.

Child Dose

Children (Older than 2 years of age): No specific studies are available in this patient group. For possible systemic effects, the dosage should exceed to 1 to 2 drops per day. Children (Below 2 years of age): Not to be used in children below 2 years of age. The eye drop should not be used for longer periods than 14 days as this may cause rebound hyperemia and toxic follicular conjunctivitis.

Renal Dose

Administration

Contra Indications

Hypersensitivity.

Precautions

Do not use on infants, young child. Prolonged use can cause rebound congestion. Discontinue if ocular pain or visual changes occur. Pregnancy, lactation.

Pregnancy-Lactation

Pregnancy No clinical data on exposed pregnancies are available. The eye drops should only be used if the potential benefits outweigh the risks to the fetus or infant. Lactation It is not known whether either of the active substances of the eye drop passes into breast milk. Caution should be exercised when using the product during breast-feeding.

Interactions

Sympathomimetic agents may cause a hypertensive crisis if used during treatment with MAOIs. Concomitant use with MAOIs is therefore contraindicated. Sedating anti-histamines can enhance the sedating effects of CNS depressants including alcohol, hypnotics, opioid analgesics, anxiolytic sedatives and anti-psychotics. They also have an additive anti-muscarinic action with other anti-muscarinic drugs, such as atropine and antidepressant

Adverse Effects

Side effects of Antazoline 0.05% + Tetryzoline 0.04% eye prep : Hypersensitivity reactions. Skin sensitization. Headache, hypertension, tremors, weakness, sweating, rebound congestion with prolonged use. Nasal: transient burning, stinging, sneezing, dryness of mucosa. Eye: blurred vision, irritation, mydriasis.

Mechanism of Action

Antazoline is an ethylenediamine-derivative antihistamine. Tetryzoline is a sympathomimetic with alpha-adrenergic activity with little or no effect on beta-adrenergic receptors.

Note

Opthamet 0.05% + 0.04% Eye Drops manufactured by Drug International Ltd.. Its generic name is Antazoline 0.05% + Tetryzoline 0.04% eye prep. Opthamet is availble in Bangladesh. Farmaco BD drug index information on Opthamet Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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