Closten Cream
Clotrimazole Topical
10 mg/gm
Alco Pharma Limited
| Pack size | 10gm tube |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 28.80 AED |
Indications
Closten Cream is used for:
Skin and nail fungal infections, Tinea pedis, Tinea cruris, Tinea corporis, Cutaneous Candidiasis, Dermatophytosis, Pityriasis versicolor
Adult Dose
Topical/Cutaneous
Skin and nail fungal infections:
Adult: Apply 2 or 3 times daily.
Onychomycosis: Apply to the affected area twice daily for 6 months.
Tinea pedis & Dermatomycoses: Apply to the affected area twice daily for 4 weeks.
Child Dose
Tinea Corporis/Tinea Pedis
Apply to the affected area twice daily for 4 weeks
Tinea Cruris
>2 years: Apply to the affected area twice daily for 2 weeks
Candidiasis
Gently massage sufficient clotrimazole into the affected and surrounding area twice daily; reconsider diagnosis if no improvement after 4 weeks
Tinea Versicolor
Gently massage sufficient clotrimazole into the affected and surrounding area twice daily; reconsider diagnosis if no improvement after 4 weeks
Renal Dose
Administration
Contra Indications
Hypersensitivity to clotrimazole or components
Precautions
Avoid contact with eyes
Some dosage forms contain benzyl alcohol; large amounts of benzyl alcohol have been associated with gasping syndrome (potentially fatal) in neonates
Not for use by patients who have never had a vaginal infection diagnosed by a doctor
Not for use with tampons, douches, spermicides, or other vaginal products
Condoms and diaphragms may damage and fail to prevent pregnancy or sexually transmitted disease
Not for use when having vaginal intercourse
May cause mild increase in vaginal burning, itching or irritation
Patient should ask doctor if symptoms do not get better in 3 days, symptoms last more than 7 days, or experience rash, abdominal pain, fever, chills, nausea, vomiting, or a foul smelling vagina discharge
Pregnancy-Lactation
Pregnancy
Small amounts of imidazoles may be absorbed systemically following topical and vaginal administration
Lactation
Excretion in milk unknown; use with caution
Interactions
Antagonism with polyene antibiotics.
Adverse Effects
Side effects of Clotrimazole Topical :
Frequency Not Defined
Blistering
Erythema
Edema
Pruritus
Burning
Stinging
Peeling
Urticaria
Skin fissures
General irritation of the skin
Elevated serum AST (SGOT) concentrations (15%)
Mechanism of Action
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Note
Closten 10 mg/gm Cream manufactured by Alco Pharma Limited. Its generic name is Clotrimazole Topical. Closten is availble in Bangladesh.
Farmaco BD drug index information on Closten Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.