Cantrim Cream

Clotrimazole Topical
1%
Rephco Pharmaceuticals Ltd.
Pack size 10 gm tube
Dispensing mode
Source
Agent
Retail Price 28.00 AED

Indications

Cantrim Cream is used for: Skin and nail fungal infections, Tinea pedis, Tinea cruris, Tinea corporis, Cutaneous Candidiasis, Dermatophytosis, Pityriasis versicolor

Adult Dose

Topical/Cutaneous Skin and nail fungal infections: Adult: Apply 2 or 3 times daily. Onychomycosis: Apply to the affected area twice daily for 6 months. Tinea pedis & Dermatomycoses: Apply to the affected area twice daily for 4 weeks.

Child Dose

Tinea Corporis/Tinea Pedis Apply to the affected area twice daily for 4 weeks Tinea Cruris >2 years: Apply to the affected area twice daily for 2 weeks Candidiasis Gently massage sufficient clotrimazole into the affected and surrounding area twice daily; reconsider diagnosis if no improvement after 4 weeks Tinea Versicolor Gently massage sufficient clotrimazole into the affected and surrounding area twice daily; reconsider diagnosis if no improvement after 4 weeks

Renal Dose

Administration

Contra Indications

Hypersensitivity to clotrimazole or components

Precautions

Avoid contact with eyes Some dosage forms contain benzyl alcohol; large amounts of benzyl alcohol have been associated with gasping syndrome (potentially fatal) in neonates Not for use by patients who have never had a vaginal infection diagnosed by a doctor Not for use with tampons, douches, spermicides, or other vaginal products Condoms and diaphragms may damage and fail to prevent pregnancy or sexually transmitted disease Not for use when having vaginal intercourse May cause mild increase in vaginal burning, itching or irritation Patient should ask doctor if symptoms do not get better in 3 days, symptoms last more than 7 days, or experience rash, abdominal pain, fever, chills, nausea, vomiting, or a foul smelling vagina discharge

Pregnancy-Lactation

Pregnancy Small amounts of imidazoles may be absorbed systemically following topical and vaginal administration Lactation Excretion in milk unknown; use with caution

Interactions

Antagonism with polyene antibiotics.

Adverse Effects

Side effects of Clotrimazole Topical : Frequency Not Defined Blistering Erythema Edema Pruritus Burning Stinging Peeling Urticaria Skin fissures General irritation of the skin Elevated serum AST (SGOT) concentrations (15%)

Mechanism of Action

Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.

Note

Cantrim 1% Cream manufactured by Rephco Pharmaceuticals Ltd.. Its generic name is Clotrimazole Topical. Cantrim is availble in Bangladesh. Farmaco BD drug index information on Cantrim Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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