Zimon Plus Syrup
Cyanocobalamin + Elemental Iron + Folic Acid
(25 mcg+100 mg+1 mg)/5 ml
Zenith Pharmaceuticals Ltd.
| Pack size | 60ml bot |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 30.00 AED |
Indications
Zimon Plus Syrup is used for:
Iron deficiency anemia, Megaloblastic anemias, গron and folic acid deficiencies during pregnancy
Adult Dose
Adults:
1-2 tsf daily.
Child Dose
Child:
1 tsf daily.
Renal Dose
Administration
Contra Indications
Hypersensitivity to folic acid, cyanocobalamin, pyridoxine, or any component of the formulation.
Conditions with high serum iron levels (hemochromatosis, hypersiderosis, chronic hemolysis).
In case of problems inherent to iron consumption (anemia of lead poisoning, sideroblastic anemia).
In case of thalassemia
Precautions
Iron chelates with antacid and tetra cycline, so there absorption may be impaired if use concurrently.
Oral iron preparations are used with caution in patients with gastritis, gastric or intestinal ulcer, Crohn's disease and ulcerative colitis.
A dark coloration of the stools can occur during the treatment with iron syrup, however it is not clinically relevant.
Patient with blood disorder.
Pregnancy-Lactation
Interactions
Cyanocobalamin: Absorption reduced by antibiotics, aminosalicylic acid, anticonvulsants, biguanides, cholestyramine, cimetidine, colchicine, K salts, methyldopa.
Elemental iron: Antacids may decrease the absorption of carbonyl iron.
Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.
Adverse Effects
Side effects of Cyanocobalamin + Elemental Iron + Folic Acid :
Iron: Constipation, diarrhea, nausea, vomiting, dark stools, and abdominal pain
Folic acid: Allergic sensitization
Bronchospasm,Flushing,Malaise,Erythema,Rash,Diarrhea,Nausea,Pruritus,Urticaria
Mechanism of Action
Vitamin B12 (cyanocobalamin): Required for the maintenance of normal erthropoiesis, nucleprotein and myelin synthesis, cell reproduction and normal growth; Coenzyme; metabolic functions include protein synthesis and carbohydrate metabolism. Plays role in cell replication and hematopoiesis.
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.
Note
Zimon Plus (25 mcg+100 mg+1 mg)/5 ml Syrup manufactured by Zenith Pharmaceuticals Ltd.. Its generic name is Cyanocobalamin + Elemental Iron + Folic Acid. Zimon Plus is availble in Bangladesh.
Farmaco BD drug index information on Zimon Plus Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.