Zalain Vaginal Suppository
Sertaconazole vaginal prep
300 mg
ZAS Corporation
| Pack size | 1's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 1150.00 AED |
Indications
Zalain Vaginal Suppository is used for:
Vaginal candidiasis
Adult Dose
Vaginal Suppository
One vaginal suppository in the evening, to be inserted deeply into the vagina, preferably while lying down.
If symptoms persist, repeat with a second vaginal suppository seven days after the first insertion.
Child Dose
Renal Dose
Administration
Contra Indications
Known hypersensitivity to any imidazole antimycotic or to any of the excipients.
Concomitant use of contraceptive diaphragm.
Precautions
Upon confirmation of diagnosis, etiological factors causing the infection should be investigated, and patients should be counseled so as to avoid future recurrence.
Use soaps which are of neutral or alkaline pH when washing the outer genitals, as lower pH favours candidiasis.
Practice good personal hygiene; wear preferably cotton underclothes; avoid vaginal douches.
If mycosis occurs on the vulvar or perianal areas, apply an antifungal cream on these areas.
Consider the treatment of sexual partner wherever applicable for each specific case.
Do not interrupt treatment during menstruation.
Concomitant treatment for any bacterial infection associated with candidiasis is advisable.
In case of local intolerance or allergic reaction, stop treatment.
Pregnancy-Lactation
Pregnancy
Studies conducted in animals have shown no teratogenic effects. Therefore there is no reason to expect malformations in humans. Up to date, no clinical evidence of any defects or foetotoxic effect of sertaconazole nitrate used during pregnancy.
Because of formulation and administration (single dose) and the absence of systemic absorption, use of sertaconazole nitrate suppository during pregnancy is possible only on medical advice and if the benefits outweigh any possible risk.
Lactation
There is no evidence of passing sertaconazole nitrate in breast milk
Interactions
The concomitant use with contraceptive diaphragm may cause the sheath or diaphragm to break during the insertion of the vaginal suppository (See Contraindications).
The concomitant use with local spermicidal contraception is not recommended as the spermicide may be inactivated.
Adverse Effects
Side effects of Sertaconazole vaginal prep :
With the absence of systemic absorption of sertaconazole after the application of a vaginal suppository, side effects are unlikely to occur.
General disorders and administration site conditions:
- manifestations of local intolerance (burning sensation or vaginal pruritus)
- possible allergic reactions
Mechanism of Action
Sertaconazole is a new local imidazole product and have broad-spectrum effect on pathogenic dimorphic fungi (Candida Albicans, C.tropicalis, C. Spp, Pityrosporum orbiculare), dermatophytes (Trychophyton, Epidermophyton and Microsporum) and other Gram-positive microbes (Staphylococcus, Streptococcus) causing infections in the skin or mucous membranes.
Note
Zalain 300 mg Vaginal Suppository manufactured by ZAS Corporation. Its generic name is Sertaconazole vaginal prep. Zalain is availble in Bangladesh.
Farmaco BD drug index information on Zalain Vaginal Suppository is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.