Uro-Vaxom Capsule
Lyophilised bacterial lysates of E. coli
6 mg
ZAS Corporation
| Pack size | 30's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 85.00 AED |
Indications
Uro-Vaxom Capsule is used for:
Urinary tract infections (UTI)
Adult Dose
Oral
Capsule
Prevention of recurrent lower urinary tract infections and co-medication in treating acute urinary tract infections.
Preventive treatment: 1 capsule once daily, preferably in the morning on an empty stomach, for 3 consecutive months (90 days).
Treatment of acute episodes: 1 capsule once daily, preferably taken in the morning on an empty stomach as co-medication to conventional antimicrobial therapy, until symptoms disappear, but for at least 10 consecutive days.
Child Dose
Oral
Capsule
Prevention of recurrent lower urinary tract infections and co-medication in treating acute urinary tract infections.
Child > 4 years
Preventive treatment: 1 capsule once daily, preferably in the morning on an empty stomach, for 3 consecutive months (90 days).
Treatment of acute episodes: 1 capsule once daily, preferably taken in the morning on an empty stomach as co-medication to conventional antimicrobial therapy, until symptoms disappear, but for at least 10 consecutive days.
Renal Dose
Administration
Should be taken on an empty stomach.
Contra Indications
Known hypersensitivity towards the constituents of Lyophilised bacterial lysates of E. coli
Precautions
The efficacy and safety of Lyophilised bacterial lysates of E. coli have not been established in children below 4 years.
Pregnancy-Lactation
Pregnancy: It is preferable to avoid the use of Lyophilised bacterial lysates of E. coli during pregnancy (Especially during the first Trimester)
Breast-feeding: Lyophilised bacterial lysates of E. coli must only be used with the advice of a doctor.
Interactions
No drug interaction is known up to now.
Adverse Effects
Side effects of Lyophilised bacterial lysates of E. coli :
Common (can affect up to 1 person in 10):
Diarrhea, nausea, headache, stomach problems, gastric intolerance.
Uncommon (can affect up to 1 person in 100):
Allergic reaction, abdominal pain, skin rash, itching, fever
Very rare (affect fewer than one person in 10000):
Swelling (edema) of the mouth, swelling of the ankles, feet or fingers, hair loss.
Mechanism of Action
Lyophilized Bacterial Lysate of Escherichia coli enhances both innate and adaptive immune responses, bolstering the body's defense against urinary pathogens.
Upon oral administration, it activates innate immune cells (phagocytes and APCs) by stimulating pattern recognition receptors (PRRs) in Peyer’s patches (GALT).
This initiates immune cell maturation, which then migrate to the urinary tract, providing localized protection.
Innate and Adaptive Immunity Enhancement:
Innate Immunity: Lyophilized Bacterial Lysate of Escherichia coli increases cytokine production, adhesion molecules, and enhances phagocytosis, contributing to a rapid defense.
Adaptive Immunity: It stimulates polyclonal lymphocyte activation, leading to IgA and IgG production, which provides humoral protection in the urinary tract, preventing recurrent urinary tract infections(UTIs).
By reinforcing immune defenses and preventing inflammation in the bladder, Lyophilized Bacterial Lysate of Escherichia coli reduces the recurrence of UTIs, offering a long-term, immunotherapeutic alternative to traditional antimicrobial treatments.
Note
Uro-Vaxom 6 mg Capsule manufactured by ZAS Corporation. Its generic name is Lyophilised bacterial lysates of E. coli. Uro-Vaxom is availble in Bangladesh.
Farmaco BD drug index information on Uro-Vaxom Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.