Thiotab Tablet
Sodium Thiosulfate
15mg
Sonear Laboratories Ltd.
| Pack size | 100's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 1.32 AED |
Available as:
Indications
Thiotab Tablet is used for:
Calcium urolithiasis, Cyanide poisoning, Secondary Preventive Treatment for Calciphylaxis in Dialysis Patients
Adult Dose
Oral
A 2 M (molar) solution can be prepared with 74.4 g in 150 mL free water; 2.6 g can be given orally daily or 3 times a week.
Dose is limited by diarrhea.
Child Dose
Renal Dose
Administration
Contra Indications
Oedematous sodium-retaining conditions.
Precautions
May irritate eyes, skin and respiratory tract.
Pregnancy-Lactation
Pregnancy Category: C
Interactions
Decreases toxicity of cisplatin through rapid chemical inactivation of its platinum component.
Adverse Effects
Side effects of Sodium Thiosulfate :
Osmotic disturbances. Oral: catharsis (at high doses).
Mechanism of Action
Thiosulfate is sulfur donor utilized by rhodenase to convert cyanide to less toxic thiocyanate.
Cisplatin toxicity: Na-thiosulfate combines w/ cisplatin to form a complex nontoxic to both normal/cancerous cells. Increases solubility of calcium.
Note
Thiotab 15mg Tablet manufactured by Sonear Laboratories Ltd.. Its generic name is Sodium Thiosulfate. Thiotab is availble in Bangladesh.
Farmaco BD drug index information on Thiotab Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.