Tendonil Capsule
Acemetacin
60 mg
Orion Pharma Ltd.
| Pack size | 30s pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 8.02 AED |
Indications
Tendonil Capsule is used for:
Rheumatoid arthritis, Osteoarthritis, Lower back pain, Ankylosing spondylitis, Post-operative pain, Musculoskeletal and joint pain
Adult Dose
Adult:
Oral
Pain and inflammation associated with musculoskeletal and joint disorders; Post-op pain 120-180 mg/day.
Child Dose
Renal Dose
Severe: Contraindicated
Administration
Should be taken with food. Take w/ or immediately after meals.
Contra Indications
Previous/active peptic ulcers; hypersensivity to aspirin/NSAIDs; severe liver disease; neonates with untreated infection, children, pregnancy, lactation.
Precautions
Elderly; allergic disorders/coagulation defects; epilepsy; parkinsonism; psychiatric disturbances (prolonged therapy may require ophthalmic and blood examinations); renal, hepatic or cardiac impairment.
Monitoring Parameters:
Monitor blood pressure, CBC, renal function and liver function.
Observe for gastrointestinal pain and bleeding.
Perform ophthalmological exams periodically during prolonged use.
Pregnancy-Lactation
Interactions
May reduce the antihypertensive effect of beta-blockers. May prolong bleeding when used with acenocoumarol. Increased risk of convulsion when used with quinolone. Concurrent use with aspirin, NSAIDs, SSRIs or corticosteroids may increase risk of GI bleeding. May increase serum levels of ciclosporin. May increase serum levels of lithium.
Potentially Fatal: Increased risk of methotrexate toxicity when used together.
Adverse Effects
Side effects of Acemetacin :
Headaches, dizziness, GI disturbances; anaemia; acute interstitial nephritis; corneal deposits, retinal disturbances; rash, urticaria; alopoecia; CHF, tachycardia, arrhythmias, palpitations; jaundice.
Potentially Fatal: Toxic hepatitis, Stevens-Johnson syndrome.
Mechanism of Action
Acemetacin is the glycolic acid ester of indometacin. It inhibits cyclooxygenase and hence prevents the formation of prostaglandins which are involved in the inflammation process.
Note
Tendonil 60 mg Capsule manufactured by Orion Pharma Ltd.. Its generic name is Acemetacin. Tendonil is availble in Bangladesh.
Farmaco BD drug index information on Tendonil Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.