Rhomex Syrup

Levamisole
40 mg/5 ml
Unique Pharmaceutical Ltd.
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Indications

Rhomex Syrup is used for: Ascariasis, Ancylostomiasis

Adult Dose

Oral Ascariasis Adult: 150 mg as a single dose. Mixed ascariasis-hookworm infections; Ancylostomiasis Adult: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases.

Child Dose

Oral Ascariasis Child: 3 mg/kg as a single dose. Mixed ascariasis-hookworm infections; Ancylostomiasis Child: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases.

Renal Dose

Administration

Should be taken with food. Take w/ meals to minimise side effects eg nausea.

Contra Indications

Preexisting blood disorders; pregnancy and lactation; rheumatoid arthritis; severe renal impairment.

Precautions

Hepatic impairment, Sjogren's syndrome.

Pregnancy-Lactation

Interactions

May increase toxicity of phenytoin. Increases bioavailability of ivermectin; decreases bioavailability of albendazole. Alcohol causes disulfiram-like reaction.

Adverse Effects

Side effects of Levamisole : Nausea, vomiting, diarrhoea, abdominal pain, dizziness and headache. Fever, influenza-like syndrome, arthralgia, muscle pain, rash, taste disturbances and cutaneous vasculitis. Potentially Fatal: Agranulocytosis, leucopenia, thrombocytopenia.

Mechanism of Action

Levamisole is the active laevo-isomer of tetramisole. It works by paralysing susceptible intestinal worms which are then excreted from the intestines. Levamisole also enhances cellular immune responses in humans.

Note

Rhomex 40 mg/5 ml Syrup manufactured by Unique Pharmaceutical Ltd.. Its generic name is Levamisole. Rhomex is availble in Bangladesh. Farmaco BD drug index information on Rhomex Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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