Ravu Capsule
Ravuconazole
100 mg
Square Pharmaceuticals PLC.
| Pack size | 10's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 300.00 AED |
Indications
Ravu Capsule is used for:
Onychomycosis
Adult Dose
Oral
Onychomycosis
1 capsule (100 mg as Ravuconazole) administered orally once daily for 12 weeks.
Child Dose
Renal Dose
Administration
Contra Indications
Known hypersensitivity (especially generalized allergic reaction) to any of the ingredients.
Precautions
Trim the lesioned nail with a file or nail clipper as necessary. If anyone is capable of becoming pregnant, be sure to use birth control while taking this medicine and for at least 3 months after discontinuing this medicine.
Pregnancy-Lactation
If anyone is capable of becoming pregnant, be sure to use birth control while taking this medicine and for at least 3 months after discontinuing this medicine.
Interactions
The therapeutic efficacy of Ravuconazole can be increased when used in combination with Amiodarone, Amlodipine, Bepridil, Cinnarizine, Clevidipine & Carvedilol.
The therapeutic efficacy of Acenocoumarol can be increased when used in combination with Ravuconazole.
Cimetidine, Calcium carbonate, Almasilate, Aluminium phosphate, Aluminum hydroxide & Asenapine can cause a decrease in the absorption of Ravuconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Adverse Effects
Side effects of Ravuconazole :
The most commonly reported adverse reactions include stomach discomfort, constipation and angular cheilitis. The symptoms described below are rarely seen as initial symptoms of the adverse reactions.
loss of appetite, nausea, jaundice [liver dysfunction]
Round or oval red rash, fever, joint pain [erythema multiforme]
Mechanism of Action
Fosravuconazole L-lysine ethanolate is a prodrug of Ravuconazole, a novel triazole antifungal agent, exerting broad and potent antifungal activity. It shows antimycotic effects by inhibiting the biosynthesis of ergosterol, which is a cellular membrane component of fungi. Ravuconazole is structurally more similar to fluconazole and voriconazole, containing a thiazole instead of a second triazole. It is usually used to treat Onychomycosis. Ravuconazole is highly active against all Aspergillus species (including A. fumigatus & A. flavus isolates), Candida spp., Cryptococcus neoformans & other yeasts, including fluconazole-resistant isolates.
Note
Ravu 100 mg Capsule manufactured by Square Pharmaceuticals PLC.. Its generic name is Ravuconazole. Ravu is availble in Bangladesh.
Farmaco BD drug index information on Ravu Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.