Pregmin Capsule
Carbonyl Iron + Folic Acid
50 mg + 500 mcg
Rangs Pharmaceuticals Ltd.
| Pack size | 50's Pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 2.41 AED |
Indications
Pregmin Capsule is used for:
Iron deficiency anemia
Adult Dose
Oral
One capsule daily.
In more severe cases, 2 capsules a day may be required
Child Dose
Renal Dose
Administration
For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation
Contra Indications
This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.
Precautions
Care should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.
Pregnancy-Lactation
Interactions
Carbonyl iron: Antacids may decrease the absorption of carbonyl iron.
Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.
Adverse Effects
Side effects of Carbonyl Iron + Folic Acid :
Iron
>10%
Constipation,Diarrhea,Nausea,Epigastric pain,Dark stools,Vomiting
Frequency Not Defined
Hemosiderosis (during long-term administration of large amounts),Urine discoloration,Dental stain by some formulations,Heartburn
Folic acid
Bronchospasm,Erythema,Malaise,Pruritus,Rash,Slight flushing
Mechanism of Action
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.
Note
Pregmin 50 mg + 500 mcg Capsule manufactured by Rangs Pharmaceuticals Ltd.. Its generic name is Carbonyl Iron + Folic Acid. Pregmin is availble in Bangladesh.
Farmaco BD drug index information on Pregmin Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.