Polytracin Eye Ointment
Bacitracin Zinc + Polymixin B Eye prep
500 IU + 10000 IU/gm
Ibn Sina Pharmaceutical Ind. Ltd.
| Pack size | 5gm tube |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 65.00 AED |
Indications
Polytracin Eye Ointment is used for:
Bacterial ocular infections
Adult Dose
Adult: Ophth Ocular infections; Prevention of ocular infection following surgical procedure:
Apply ½ inch 3-4 hrly for acute infections or 2-3 times/day for mild-to-moderate infections for 7-10 days.
Treatment should be continued for another 2 days after the eye has apparently recovered.
Child Dose
Child: Apply ½ inch ribbon in the affected eye(s) every 3-4 hr for acute infections or 2-3 times/day for mild-to-moderate infections for 7-10 days. Treatment should be continued for another 2 days after the eye has apparently recovered.
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Ointment may blur vision. Prolonged use of the antibacterial preparation may cause overgrowth of non-susceptible organisms, including fungi. Pregnancy and lactation.
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Excretion in breast milk unknown; use caution
Interactions
Bacitracin Zinc: Increased risk of nephrotoxicity when used with other nephrotoxic drugs. May enhance the action of neuromuscular-blocking agents.
Polymixin B: Potentially Fatal: Additive neurotoxic or nephrotoxic effect w/ bacitracin, streptomycin, neomycin, kanamycin, gentamicin, tobramycin, amikacin, cephaloridine, paromomycin, viomycin, colistin. Increased risk of resp paralysis w/ neuromuscular blockers (e.g. anaesthetics, muscle relaxants).
Adverse Effects
Side effects of Bacitracin Zinc + Polymixin B Eye prep :
<1%
Allergic contact dermatitis,Conjunctival erythema,Swelling,Itching,Burning
Mechanism of Action
Bacitracin, inhibits bacterial cell wall synthesis and is active against many gram-positive bacteria (e.g. staphylococci, streptococci, corynebacteria and clostridia) and some gram-negative species (e.g. Neisseria and Haemophilus influenzae).
They are often found in combinations in topical preparations as broad spectrum antibacterial agents. Polymyxin B disrupts the bacterial cytoplasmic membrane of mostly gm-ve organisms allowing leakage of intracellular constituents by binding to membrane phospholipids.
Note
Polytracin 500 IU + 10000 IU/gm Eye Ointment manufactured by Ibn Sina Pharmaceutical Ind. Ltd.. Its generic name is Bacitracin Zinc + Polymixin B Eye prep. Polytracin is availble in Bangladesh.
Farmaco BD drug index information on Polytracin Eye Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.