Pidomod Tablet
Pidotimod
400 mg
General Pharmaceuticals Ltd.
| Pack size | 20's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 35.00 AED |
Available as:
Indications
Pidomod Tablet is used for:
Immunostimulant in respiratory tract or urinary tract infections, recurrent upper and lower respiratory tract infections, acute respiratory tract infections, asthma, chronic obstructive pulmonary disorders, chronic bronchitis, and immunological disorders.
Adult Dose
Oral
Tablet
Immunostimulant in respiratory tract or urinary tract infections, recurrent upper and lower respiratory tract infections, acute respiratory tract infections, asthma, chronic obstructive pulmonary disorders, chronic bronchitis, and immunological disorders.
Adult:
Acute Phase: First: 8 days 800 mg bid.
Prevention: Rest 60 days 400 mg once daily
Child Dose
Children >3 years:
First 15 days 400 mg twice daily
Rest 45 days 400 mg once daily
Pidotimod is not recommended for use in children less than 2 years of age since the safety and efficacy of use are not clinically established.
Renal Dose
This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary to safely use this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Administration
Take the tablet at the same time, with or without food.
Contra Indications
Hypersensitivity
Patients with a known allergy to pidotimod or any other inactive ingredients present in the formulation.
Precautions
This medicine is not recommended for use in children less than 3 years of age since the safety and efficacy of use are not clinically established. It should be used with caution in patients less than 18 years of age and only under the supervision of a qualified healthcare professional.
Pregnancy-Lactation
Not studied in Pregnant women.
This medicine is not recommended for use in pregnant women unless necessary.
This medicine is not recommended for use in breastfeeding women unless necessary.
Interactions
Adverse Effects
Side effects of Pidotimod :
Nausea and Vomiting
Diarrhea
Abdominal pain
Dry mouth
Loss of appetite
Skin rash.
Mechanism of Action
Pidotimod inhibits tumor necrosis factor α (TNF-α) induced increases in extracellular signal-related kinase (ERK) phosphorylation 2. It also increases nuclear factor κB (NFκB) expression and translocation to the nucleus. It is these to modulatory effects on ERK and NFκB signalling which are thought to produce the increase in toll-like receptor expression seen with pidotimod.
Pidotimod increase maturation of dendritic cells responsible for presenting antigens to naive Th-cells. It also appears to result in a greater population these cells diiferentiating to Th1 cells which are believed to mediate the immune response to pathogens like bacteria and viruses.
Lastly, pidotimod appears to increase antigen-specific antibody titer and cytotoxic response with antigen exposure. The precise mechanism and timeline of events leading to these effects is unknown.
Note
Pidomod 400 mg Tablet manufactured by General Pharmaceuticals Ltd.. Its generic name is Pidotimod. Pidomod is availble in Bangladesh.
Farmaco BD drug index information on Pidomod Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.