Oryza Mouth Wash
Benzydamine Mouth prep
0.15%w/v
Incepta Pharmaceuticals Ltd.
| Pack size | 120ml,250ml |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 120.00,225.00 AED |
Indications
Oryza Mouth Wash is used for:
Pain or irritation of the mouth and throat, Acute Pharyngitis, Radiation-Associated Mucositis
Adult Dose
Mouth/Throat
Pain or irritation of the mouth and throat, Acute pharyngitis
Adult: Rinse or gargle 15 ml of a 0.15% solution (diluted with water if stinging occurs) every 1½ to 3 hours until remission of pain..
Radiation-Associated Mucositis
Gargle or rinse 15 mL in mouth (for 30 seconds, followed by expulsion from mouth) 3-4 times per day
Begin treatment 1 day prior to radiation therapy and continue daily during treatment
Child Dose
Child
13–17 years: Rinse or gargle 15 mL every 1.5–3 hours as required usually for not more than 7 days, dilute with an equal volume of water if stinging occurs
Renal Dose
Administration
Rinse the 15 ml mouthwash around the mouth or use it as a gargle. After 20 to 30 second, spit it out. Do not swallow the mouthwash.
Contra Indications
Benzydamine Hydrochloride is contraindicated in subjects with a history of hypersensitivity to any of its components.
Precautions
The use of undiluted benzydamine Hydrochloride may produce local irritation manifested by burning sensation in patients with mucosal defects. If necessary, it may be diluted (1:1) with lukewarm water. Since it is absorbed from the oral mucosa and excreted mostly unchanged in the urine, a possibility of its systemic action has to be considered in patients with renal impairment.
Pregnancy-Lactation
Pregnancy Category: Not available. Safety has not been established in pregnant women.
Lactation: excretion in milk unknown; use with caution
Interactions
Adverse Effects
Side effects of Benzydamine Mouth prep :
1-10%
Burning /stinging sensation,Nausea/vomiting,Numbness
Frequency Not Defined
Cough,Drowsiness,Dry mouth,Headache,Pharyngeal irritation
Mechanism of Action
Benzydamine Hydrochloride predominantly acts by inhibiting the synthesis of pro inflammatory cytokines like tumour necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β) without largely affecting other pro inflammatory cytokines. Moreover, it is capable of a local anaesthetic effect that may be related to its capability for inhibiting the release of inflammatory mediators like substance P.
Note
Oryza 0.15%w/v Mouth Wash manufactured by Incepta Pharmaceuticals Ltd.. Its generic name is Benzydamine Mouth prep. Oryza is availble in Bangladesh.
Farmaco BD drug index information on Oryza Mouth Wash is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.