Optaphenicol Eye Ointment

Chloramphenicol 1% Eye prep

1 gm/100 gm

Reman Drug Laboratories Ltd.

Pack size	3gm tube
Dispensing mode
Source
Agent
Retail Price	10.00 AED

Indications

Optaphenicol Eye Ointment is used for: Bacterial Conjunctivitis

Adult Dose

Ocular infections Adult: Apply a 1% ointment 3-4 times daily.

Child Dose

Renal Dose

Renal impairment: Dose reduction may be required.

Administration

Contra Indications

History of hypersensitivity to the drug; Herpes simplex and other virul conditions of the eye, mycosis.

Precautions

Avoid prolonged use. Discontinue immediately if local hypersensitivity reactions occur.

Pregnancy-Lactation

Interactions

Decreased effects of iron and vitamin B12 in anaemic patients. Phenobarbitone and rifampin reduce efficacy of chloramphenicol. Impairs the action of oral contraceptives. Potentially Fatal: Increases the effect of oral anticoagulants, oral hypoglycaemic agents, phenytoin. Avoid concomitant administration with drugs that depress bone marrow function.

Adverse Effects

Side effects of Chloramphenicol 1% Eye prep : Ophthalmic application: Hypersensitivity reactions including rashes, fever and angioedema.

Mechanism of Action

Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase. It has both bacteriostatic and bactericidal action against H. influenzae, N. meningitidis and S. pneumoniae.

Note

Optaphenicol 1 gm/100 gm Eye Ointment manufactured by Reman Drug Laboratories Ltd.. Its generic name is Chloramphenicol 1% Eye prep. Optaphenicol is availble in Bangladesh. Farmaco BD drug index information on Optaphenicol Eye Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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