Onecal-M Tablet
Calcium + Vitamin D + Multiminerals
One Pharma Ltd.
| Pack size | 30's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 6.50 AED |
Indications
Onecal-M Tablet is used for:
Osteoporosis, Calcium deficiency, Post-menopausal osteoporosis, Rickets, Osteocalcaemia, Mineral supplement
Adult Dose
Adults:
2 tablets per day, preferably one tablet each morning and evening.
Child Dose
Children above 12 years of age:
2 tablets per day, preferably one tablet each morning and evening.
Not recommended for children under 12 years.
Renal Dose
Administration
Contra Indications
Patients with a known hypersensitivity to any of the ingredients.
Precautions
Patients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully.
Urinary calcium excretion should also be measured. In patients with a history of renal stones urinary calcium excretion should be measured to exclude hypercalciuria.
With long-term treatment, it is advisable to monitor serum and urinary calcium levels and kidney function and reduce or stop treatment temporarily if urinary calcium exceeds 7.5mmol/24 hours.
MONITORING PARAMETERS
Periodic checks of plasma calcium levels and urinary calcium excretion should be made in patients with mild to moderate renal failure or mild hypercalciuria.
Monitor ECG and serum calcium levels.
Pregnancy-Lactation
Interactions
It has possible interaction with digoxin, antacids containing calcium, aluminum or magnesium, other calcium supplements, calcitriol or other Vitamin-D supplements; tetracycline, Doxycycline, aminocycline or oxytetracycline etc
May affect the absorption of tetracycline when used together.
Concurrent use with systemic corticosteroids may reduce calcium absorption.
Thiazide diuretics may decrease urinary excretion of calcium.
Concurrent use with ion-exchange resins may reduce GI absorption of vitamin D.
Hypercalcaemia may increase the toxicity of cardiac glycosides during treatment with calcium and vitamin D.
Bisphosphonate or sodium fluoride should be given at least 3 hr before calcium-containing preparations.
Adverse Effects
Side effects of Calcium + Vitamin D + Multiminerals :
Mild and transient effects of gastrointestinal disturbances, like constipation, flatulence, nausea, diarrhoea may be seen in some individuals.
Following administration of vitamin D supplements may cause skin rash in some rare cases.
Hypercalciuria have been seen with long term use at high dosage.
Mechanism of Action
Calcium is used to prevent or treat negative calcium balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways.
Vitamin D is also essential for healthy bones as it aids in Calcium absorption from the GI tract. In addition to this it stimulates bone formation. Clinical studies also show that Calcium and Vitamin D has synergistic effects on bone growth as well as in Osteoporosis and fracture prevention.
Note
Onecal-M Tablet manufactured by One Pharma Ltd.. Its generic name is Calcium + Vitamin D + Multiminerals. Onecal-M is availble in Bangladesh.
Farmaco BD drug index information on Onecal-M Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.