NEO DP Eye Drops
Dexamethasone + Neomycin + Polymixin B eye prep
1 mg+3500 IU+6000 IU
Drug International Ltd.
| Pack size | 5 ml drop |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 90.30 AED |
Indications
NEO DP Eye Drops is used for:
Bacterial eye infections, Ocular inflammation
Adult Dose
Ophthalmic
Ocular inflammation with suspected or confirmed bacterial infection
Adult: Eye drops: Instill 1-2 drops in the conjunctival sac(s) of the affected eye(s) up to 4-6 times daily; may be used hourly in severe disease.
Reduce frequency once the condition improves.
Child Dose
Safety and effectiveness in pediatric patients have not been established.
Renal Dose
Administration
Contra Indications
Hypersensitivity. Epithelial herpes simplex keratitis (dentritic keratitis), vaccinia, varicella, and many other viral diseases of the cornea and conjunctiva. Hypersensitivity to a component of the medication (Hypersensitivity to the antibiotic component occurs at a higher rate than other component).
The use of these combinations is always contraindicated after uncomplicated removal of a corneal foreign body.
Precautions
Monitor intraocular pressure if used >10 days
Prolonged use of topical anti-bacterial agents may give rise to overgrowth of nonsusceptible organisms including fungi
Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and in posterior subcapsular cataract formation
Prolonged use may also suppress the host immune response and thus increase the hazard of secondary ocular infections
Various ocular diseases and long-term use of topical corticosteroids have been known to cause corneal and scleral thinning, possibly leading to perforation
Acute purulent infections of the eye may be masked or activity enhanced by the presence of corticosteroid medication
Products containing neomycin sulfate may cause cutaneous sensitization; sensitivity to topically administered aminoglycosides, such as neomycin, may occur in some patients; severity of hypersensitivity reactions may vary from local effects to generalized reactions such as erythema, itching, urticaria, skin rash, anaphylaxis, anaphylactoid reactions, or bullous reactions; discontinue if hypersensitivity occurs
Acute purulent or parasitic infections of eye may be masked or activity enhanced by presence of corticosteroid medication
Pregnancy-Lactation
Pregnancy
Dexamethasone shown to be teratogenic in mice and rabbits following topical ophthalmic application in multiples of therapeutic dose
In mouse, corticosteroids produce fetal resorptions and a specific abnormality, cleft palate; in the rabbit, corticosteroids have produced fetal resorptions and multiple abnormalities involving head, ears, limbs, palate, etc
There are no adequate or well-controlled studies in pregnant women; however, prolonged or repeated corticoid use during pregnancy associated with increased risk of intra-uterine growth retardation; neomycin and polymyxin B sulfates and dexamethasone ophthalmic suspension should be used during pregnancy only if potential benefit to mother justifies potential risk to embryo or fetus; infants born of mothers who have received substantial doses of corticosteroids during pregnancy should be observed carefully for signs of hypoadrenalism
Lactation
Systemically administered corticosteroids appear in human milk, could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects; not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk; because many drugs are excreted in human milk, caution exercise caution when drug administered to a nursing woman
Interactions
Adverse Effects
Side effects of Dexamethasone + Neomycin + Polymixin B eye prep :
Frequency Not Defined
Blurred vision
Cataract
Raised intraocular pressure
Stinging
Conjunctival hemorrhage
Glaucoma
Vitreous detachment
Hives
Rash
Itching
Eye pain
Mechanism of Action
Dexamethasone is a corticosteroid with mainly glucocorticoid activity; it is used topically mainly for its anti-inflammatory action.
Neomycin is a broad-spectrum aminoglycoside antibiotic that is used topically for the treatment of infections of the skin, ear and eye due to susceptible staphylococci and other organisms.
Polymyxin B is active only against gram-negative bacteria, especially Pseudomonas aeruginosa.
Note
NEO DP 1 mg+3500 IU+6000 IU Eye Drops manufactured by Drug International Ltd.. Its generic name is Dexamethasone + Neomycin + Polymixin B eye prep. NEO DP is availble in Bangladesh.
Farmaco BD drug index information on NEO DP Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.