Mydripine Eye Drops
Atropine eye prep
G. A. Company Ltd.
| Pack size | 10 ml bot |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 25.89 AED |
Available as:
Indications
Mydripine Eye Drops is used for:
Keratitis, iritis, cyclitis, & refractive procedure in children. Mydriatic & cycloplegic. Childhood myopia
Adult Dose
Ophthalmic
Inflammatory eye disorders
Adult: Instill 1-2 drops of a 1% solution up to 4 times daily.
Ointment: as required.
Eye refraction
Adult: Instill 1 drop of a 1% solution bid for 1-2 days before the procedure, or on a single occasion 1 hr before the procedure.
Child Dose
Ophthalmic
Child > 3 months
Inflammatory eye disorders
Child: As 1% solution: Instill 1 drop of a 1% solution up to tid.
Ointment: as required.
Slows the progression of childhood myopia
Child: As 0.01% solution: Instill 1 drop once daily on the affected eye.
Generally, the treatment is recommended for a minimum of two years. However, it can be continued up to the age of 12 or until the child's eye growth stabilizes.
Eye refraction
Child: As 0.5% - 1% solution: Instill 1 or 2 drops of a 0.5% soln (or 1 drop of a 1% solution) bid for 1-3 days before the procedure, with a further dose given 1 hr before the procedure.
Renal Dose
Administration
Contra Indications
Hypersensitivity or known allergic reaction to any ingredient of the formulation
Narrow-angle glaucoma.
Precautions
Photophobia and blurred vision due to pupil unresponsiveness and cycloplegia may last up to 2 weeks.
The risk of blood pressure increases from systemic absorption.
Increased adverse drug reaction susceptibility with certain central nervous system conditions.
Pregnancy-Lactation
Pregnancy
There are no adequate and well-controlled studies in pregnant women to inform a drug-associated risk; adequate animal development and reproduction studies have not been conducted with atropine sulfate; in humans, 1% atropine sulfate is systemically bioavailable following topical ocular administration; the drug should only be used during pregnancy if the potential benefit justifies potential risk to fetus
Lactation
There is no information to inform risk regarding presence of drug in human milk following ocular administrations of the drug to the mother; effects on breastfed infants and effects on milk production are also unknown
Developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for the drug and any potential adverse effects on breastfed child from the drug
Interactions
Additive anticholinergic effects with quinidine, antidepressants and some antihistamines.
The use of atropine and monoamine oxidase inhibitors (MAOI) is generally not recommended because of the potential to precipitate hypertensive crisis.
Adverse Effects
Side effects of Atropine eye prep :
Frequency Not Defined
Local irritation
Hyperemia
Edema
Dry eyes
Exudate
Follicular conjunctivitis
Vascular congestion
Dermatitis
Blurred vision
Hyperreactive response in Down's syndrome children (atropine)
Drowsiness
Increased intraocular pressure
Physostigmine
Mechanism of Action
Blocks the action of acetylcholine resulting in relaxation of the cholinergically innervated sphincter muscle of the iris
Cholinergic stimulation of the accommodative ciliary muscle of the lens is also blocked
Anticholinergic effects of atropine sulfate in the eye produce dilation of the pupil (mydriasis) and paralysis of accommodation (cycloplegia)
Note
Mydripine Eye Drops manufactured by G. A. Company Ltd.. Its generic name is Atropine eye prep. Mydripine is availble in Bangladesh.
Farmaco BD drug index information on Mydripine Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.