Expilin Tablet
Chlorpheniramine Maleate
4mg
G. A. Company Ltd.
| Pack size | 500's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 0.2 AED |
Available as:
Indications
Expilin Tablet is used for:
Urticaria, Sneezing, Watery eyes, Allergic conditions, Anaphylactic shock, Rhinitis, Itching
Adult Dose
Oral
Adult: 4 mg every 4-6 hr. Max: 24 mg daily.
Parenteral
Adjunct in the emergency treatment of anaphylactic shock
Adult: 10-20 mg IM, SC, or slow IV inj over 1 min. Max dose: 40 mg daily.
Child Dose
Oral
Child: 1-2 yr: 1 mg bid,
2-5 yr: 1 mg every 4-6 hr,
6-12 yr: 2 mg every 4-6 hr.
Max: 6 mg daily (1-5 yr); 12 mg daily (6-12 yr).
Parenteral
Adjunct in the emergency treatment of anaphylactic shock
Child: 87.5 mcg/kg SC 4 times daily
Renal Dose
Administration
Contra Indications
Hypersensitivity, Neonates.
Precautions
Elderly, pylori duodenal obstruction, angle-closure glaucoma, urinary retention, prostatic hyperplasia, epilepsy, renal and hepatic impairment. May affect performance of skilled tasks. BPH, bladder neck obstruction, hypertension. Pregnancy, lactation.
Pregnancy-Lactation
Pregnancy
Antihistamine exposure in first trimester not reported to be associated with increased risk of malformations; animal studies not reported; there are no controlled data in human pregnancy; only recommended for use during pregnancy when benefit outweighs risk
Lactation
Excretion into human milk; the manufacturer recommends that caution be used when administering chlorpheniramine to nursing women; infants should be monitored for irritability or drowsiness; antihistamines may temporarily decrease maternal serum prolactin concentrations when administered prior to nursing infant for the first time
Interactions
Potentiates sedative effect of psychotropic drugs e.g. barbiturates, hypnotics, opioid analgesics, anxiolytics and antipsychotics.
Interaction with alcohol could be dangerous (sedation/excitation).
Contraindicated (0)
Serious (29)
apalutamide
benzhydrocodone/acetaminophen
buprenorphine subdermal implant
buprenorphine transdermal
buprenorphine, long-acting injection
calcium/magnesium/potassium/sodium oxybates
eluxadoline
fentanyl
fentanyl intranasal
fentanyl iontophoretic transdermal system
fentanyl transdermal
fentanyl transmucosal
fexinidazole
idelalisib
isocarboxazid
lonafarnib
methohexital
metoclopramide intranasal
oliceridine
olopatadine intranasal
opicapone
remifentanil
sodium oxybate
sofpironium topical
tolcapone
tranylcypromine
tucatinib
zolpidem
zuranolone
Adverse Effects
Side effects of Chlorpheniramine Maleate :
CNS depression, sedation, drowsiness, lassitude, dizziness. GI upsets, anorexia, or increased appetite, epigastric pain, blurring of vision, dysuria, dryness of mouth, tightness in chest, hypotension, muscular weakness, tinnitus, euphoria, headache, paradoxical CNS stimulation.
Potentially Fatal: CV collapse and respiratory failure.
Mechanism of Action
Chlorphenamine is an H1-receptor antagonist which competetively blocks H1-receptor sites on tissues.
Note
Expilin 4mg Tablet manufactured by G. A. Company Ltd.. Its generic name is Chlorpheniramine Maleate. Expilin is availble in Bangladesh.
Farmaco BD drug index information on Expilin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.