Epastat Tablet

Epalrestat
50 mg
Opsonin Pharma Limited
Pack size
Dispensing mode
Source
Agent
Retail Price 10.00 AED

Indications

Epastat Tablet is used for: Diabetic neuropathy

Adult Dose

Oral Diabetic neuropathy Adult: 50 mg tid.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity. Pregnant or breastfeeding.

Precautions

Urine may turn yellowish brown or reddish after taking the medicine, because the yellowish brown or reddish color is attributed to components of this medicine.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Epalrestat : The most commonly reported adverse reactions include abdominal pain, nausea, rash, itch, erythema and blister.

Mechanism of Action

Epalrestat is aldose reductase inhibitor. The aldose reductase inhibitors have a distinct mechanism of action, affecting the underlying disease process in diabetic neuropathy, although the extent of the polyol pathway involvement is yet to be determined. Epalrestat reduces sorbitol accumulation in the sciatic nerve, erythrocytes. Epalrestat may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms.

Note

Epastat 50 mg Tablet manufactured by Opsonin Pharma Limited. Its generic name is Epalrestat. Epastat is availble in Bangladesh. Farmaco BD drug index information on Epastat Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Epalrestat :