E Cof Plus Syrup
Dextromethorphan + Guaifenesin
(100 mg+1.1 mg+14 mg)/5 m
Edruc Ltd.
| Pack size | 100 ml bot |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 80.00 AED |
Indications
E Cof Plus Syrup is used for:
Dry Cough, Chest Congestion
Adult Dose
Cough
Indicated for temporary control of cough due to minor throat and bronchial irritation
General Guidelines:
200-400 mg guaifenesin and 10-20 mg dextromethorphan 4-hourly; not to exceed 2400 mg guaifenesin and 120 mg dextromethorphan
1-2 tablets 12 hourly; not to exceed 4 tablets/24 hours
10 mL PO q4hr; not to exceed 6 doses/24 hours
Child Dose
Cough
Indicated for temporary control of cough due to minor throat and bronchial irritation
6-12 years
1 tablet PO q12hr; not to exceed 2 tablets/24 hours
5 mL PO q4hr; not to exceed 6 doses/24 hours
>12 years
1 or 2 tablets every 12 hours and not more than 4 tablets daily.
10 mL PO q4hr; not to exceed 6 doses/24 hr
Renal Dose
Administration
This product can be administered without regard for timing of meals
Do not crush, chew, or break tablet
Take with a full glass of water
Contra Indications
Both drugs contraindicated in documented hypersensitivity to either drug or components
Not for persistent cough associated with chronic bronchitis, smoking, asthma, or accompanied with excessive secretions
Within 14 days of taking MAO inhibitor
Precautions
Do not use
for children under 12 years of age
if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Dextromethorphan
Do not take for persistent or chronic cough associated with smoking, asthma, or emphysema, or if it is accompanied by excessive phlegm unless directed by a healthcare provider; may slow respiration rate
Hallucinations, confusion, agitation, hyper-reflexia, shivering, myoclonus, and tachycardia may occur
Caution in children younger than 6 years
Not for OTC use in children <4 years
Use caution in patients who are sedated, debilitated or confined to supine position
Guaifenesin
Guaifenesin is not for administration in persistent cough associated with chronic bronchitis, smoking, asthma, or accompanied with excessive secretions
Pregnancy-Lactation
Pregnacy Category: C
Lactation: excretion in milk unknown; use with caution
Interactions
Contraindicated (7)
isocarboxazid
phenelzine
procarbazine
rasagiline
safinamide
selegiline
tranylcypromine
Adverse Effects
Side effects of Dextromethorphan + Guaifenesin :
Frequency Not Defined
Dizziness
Drowsiness
Headache
Nausea
Vomiting
Mechanism of Action
Guaifenesin (Cough expectorant) increases respiratory tract fluid secretions and helps to loosen phlegm and bronchial secretions.
Dextromethorphan is a Cough suppressant that acts centrally on the cough center in the medulla.
Note
E Cof Plus (100 mg+1.1 mg+14 mg)/5 m Syrup manufactured by Edruc Ltd.. Its generic name is Dextromethorphan + Guaifenesin. E Cof Plus is availble in Bangladesh.
Farmaco BD drug index information on E Cof Plus Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.