Dilator Tablet

Bambuterol Hydrochloride
10mg
Eskayef Pharmaceuticals Ltd.
Pack size 100's pack
Dispensing mode
Source
Agent
Retail Price 3.00 AED

Indications

Dilator Tablet is used for: Chronic obstructive pulmonary disease (COPD), Asthma.

Adult Dose

Adult: PO 10-20 mg once daily at bedtime.

Child Dose

Children 2-5 years: The recommended normal dose 10 mg (10 ml syrup). Children 6-12 years: The recommended normal dose 10 mg (10 ml syrup). The dose may be increased to 20 mg.

Renal Dose

Renal impairment: CrCl (ml/min) <50 Initial dose should be halved.

Administration

Contra Indications

Severe hepatic impairment; cirrhosis.

Precautions

DM, hyperthyroidism, myocardial insufficiency, arrhythmias, susceptibility to QT-interval prolongation. Pregnancy.

Pregnancy-Lactation

Although no teratogenic effects have been observed in animals after administration of bambuterol, caution is recommended during the first trimester of pregnancy. It is not known whether bambuterol or intermediary metabolites pass over to breast milk, so caution is recommended if bambuterol is administered to patients who are breast feeding. Terbutalin passes over to breast milk but an influence on the child is unlikely with therapeutic doses. Transient hypoglycemia has been reported in newborn pre-term infants after maternal ß2 agonist treatment.

Interactions

Risk of hypokalaemia increased by co-admin of corticosteroids, diuretics or xanthines. Prolong the action of drugs e.g. suxamethonium.

Adverse Effects

Side effects of Bambuterol Hydrochloride : Fine tremor of skeletal muscle (e.g. hands), palpitations and muscle cramps; tachycardia, tenseness and peripheral vasodilation.

Mechanism of Action

Bambuterol HCl is a prodrug of terbutaline. It relaxes bronchial smooth muscle by selectively acting on ?2-receptors.

Note

Dilator 10mg Tablet manufactured by Eskayef Pharmaceuticals Ltd.. Its generic name is Bambuterol Hydrochloride. Dilator is availble in Bangladesh. Farmaco BD drug index information on Dilator Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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