Dexon Eye Ointment
Dexamethasone 0.05% Eye ointment
0.05 gm/100 gm
Ibn Sina Pharmaceutical Ind. Ltd.
| Pack size | 3 gm tube |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 65.00 AED |
Indications
Dexon Eye Ointment is used for:
Steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe, such as conjunctivitis, keratitis, iritis, scleritis, corneal injury from chemical or thermal burns, or penetration of foreign bodies. It is also effective post-operatively.
Adult Dose
Ophthalmic Ointment
Ocular inflammation
Adult: As 0.05% ointment: Apply 0.5-1 inch ribbon of ointment into the conjunctival sac(s) 3 - 4 times daily.
When a favourable response is observed, reduce the number of daily applications to twice and later to once a day as a maintenance dose if this is sufficient to control symptoms.
Child Dose
Safety and efficacy not established
Renal Dose
Administration
Contra Indications
Patients wearing contact lenses, herpes simplex & other virus conditions, mycosis, glaucoma, new born babies, fungal diseases of ocular or auricular structures, hypersensitivity to any component of this product.
Precautions
If no improvement is observed after 7-8 days, other therapeutic measures should be considered.
Corticosteroids may mask, activate or exacerbate eye infections.
Due to the risk of systemic response the administration to the children under 2, and to hyper or-hypotonics is not advisable.
During treatment the intraocular pressure should be measured regularly.
Prolonged use may result intraocular hypertension and/or glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation.
Patients wearing contact lenses must not use the drops during the time the lenses are worn.
Pregnancy-Lactation
Pregnancy
There are no adequate or well-controlled studies in pregnant women; should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the embryo or fetus
However, prolonged or repeated corticoid use during pregnancy has been associated with an increased risk of intra-uterine growth retardation
Lactation
Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects
Unknown whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk
Interactions
Adverse Effects
Side effects of Dexamethasone 0.05% Eye ointment :
Cataract (4% )
Ocular hypertension, Open-angle glaucoma, optic nerve damage, and defects in visual acuity and field of vision (after prolonged use)
<1%
Transient ocular stinging, burning, local irritation, ocular discharge, ocular discomfort or pain, foreign body sensation, hyperemia, abnormal vision/blurring, pruritus, lid margin crusting, sticky sensation, increased fibrin, dry eye, conjunctival edema, corneal staining, keratitis, tearing, edema, irritation, corneal ulcer, browache, eyelid erythema, corneal edema, infiltrate, corneal erosion, mydriasis, ptosis, epithelial punctate keratitis, and possible corneal or scleral malacia, [posterior subcapsular cataracts] (prolonged use)
Mechanism of Action
Dexamethasone is a synthetic glucocorticoid which decreases inflammation by inhibiting the migration of leukocytes and reversal of increased capillary permeability. It suppresses normal immune response.
Note
Dexon 0.05 gm/100 gm Eye Ointment manufactured by Ibn Sina Pharmaceutical Ind. Ltd.. Its generic name is Dexamethasone 0.05% Eye ointment. Dexon is availble in Bangladesh.
Farmaco BD drug index information on Dexon Eye Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.