Costin Tablet
Calcium Carbonate
500mg
General Pharmaceuticals Ltd.
| Pack size | 100's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 4.00 AED |
Available as:
Indications
Costin Tablet is used for:
Calcium deficiency, Hypocalcaemia, Osteoporosis, Hyperphosphatemia, Calcium supplement, Heartburn, Indigestion
Adult Dose
Adult:
Prevention of Osteoporosis
500-1500 mg calcium daily is recommended in general
Hyperphosphataemia in Chronic renal failure
Recommended daily dose of calcium is 1200-1500 mg.
In chronic renal failure the doses used vary from 2.5 - 9.0 gm Calcium Carbonate per day and need to be adjusted.
Antacid
Indicated to relieve heartburn, acid indigestion, sour stomach, or upset stomach associated with these symptoms
540-2000 mg Calcium Carbonate per day
Chewable tablets
Chew 2-3 tablets as symptoms occur.
Do not take >6 tablets/24 hr; pregnant females should not take >4 tablets/24 hr
Child Dose
Renal Dose
Renal impairment:
CrCl (ml/min)
<25 Dosage adjustments may be needed depending on serum calcium levels.
Administration
May be taken with or without food. Take w/ meals for better absorption. Avoid taking w/ large amount of fibre-rich food.
Contra Indications
Patients with Ca renal calculi or history of renal calculi; hypercalcaemia; hypophosphataemia. Patients with suspected digoxin toxicity.
Precautions
Bloating, gas, and constipation may occur with therapy
Hypercalcemia may occur from long-term use, which may exacerbate nephrolithiasis or cause generalized soft tissue and vascular calcification; may also increase mortality in patients with chronic kidney disease
Drug administration impaired by achlorhydria, common in the elderly; consider using an alternate salt form of calcium
Hypercalciuria and hypercalcemia may occur in patients with hypoparathyroid disease, receiving high doses of vitamin D
Kidney stones reported with use; exercise caution in patients with history
Use caution in patients with renal insufficiency; patients more susceptible to effects of excess calcium
Advise patients to limit intake of oxalate-rich foods (soy; green, leafy vegetables; animal protein) to avoid reduced absorption through Ca-oxalate formation
Pregnancy-Lactation
Pregnancy category: C
Lactation: Safe; crosses the placenta; appears in breast milk
Interactions
Co-administration with thiazide diuretics or vit D may lead to milk-alkali syndrome and hypercalcaemia. Decreased absorption with corticosteroids. Decreases absorption of tetracyclines, atenolol, iron, quinolones, alendronate, Na fluoride, Zn and calcium-channel blockers. Enhances cardiac effects of digitalis glycosides and may precipitate digitalis intoxication.
Contraindicated (1)
ceftriaxone
Serious (21)
atazanavir
baloxavir marboxil
dapsone
dasatinib
demeclocycline
digoxin
doxycycline
eltrombopag
erdafitinib
infigratinib (DSC)
ketoconazole
levoketoconazole
minocycline
nimodipine
nisoldipine
nitrendipine
oxytetracycline
pazopanib
ponatinib
sotorasib
tetracycline
Adverse Effects
Side effects of Calcium Carbonate :
Frequency Not Defined
Anorexia
Constipation
Flatulence
Nausea
Vomiting
Hypercalcemia
Hypophosphatemia
Milk-alkali syndrome
Mechanism of Action
Calcium carbonate can neutralise gastric acid rapidly and effectively. However, it may adversely activate Ca dependent processes, leading to secretion of gastric and hydrochloric acid. It can induce rebound acid secretion and, prolonged high doses may cause hypercalcemia, alkalosis and milk-alkali syndrome.
Note
Costin 500mg Tablet manufactured by General Pharmaceuticals Ltd.. Its generic name is Calcium Carbonate. Costin is availble in Bangladesh.
Farmaco BD drug index information on Costin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.