Clori HC Cream
Clotrimazole + Hydrocortisone Topical
1%+1%
Amulet Pharmaceuticals Ltd.
| Pack size | 10gm |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 35.00 AED |
Indications
Clori HC Cream is used for:
Athlete's foot, Tinea pedis, Candida nappy rash, Fungal infections, Jock itch, Ringworm, Tinea cruris, Tinea corporis
Adult Dose
Topical/Cutaneous
Inflammatory skin fungal infections
Adult: As cream: Apply thinly and evenly to the affected area bid and rub in gently.
Max duration: 7 days.
Max: 10 mg/kg; 500 mg for 50 kg adult equivalent to approx 2 cm to be divided into 2 applications per day.
Child Dose
Child: Require shorter course of treatment.
Renal Dose
Renal Impairment
The minimum quantity should be used for the shortest duration to achieve the desired clinical benefit.
Administration
Contra Indications
In patients with a known history of hypersensitivity to hydrocortisone, clotrimazole or any components of the formulation
in tuberculous conditions of the skin, acute Herpes simplex, vaccinia, varicella and all viral infections
in primary infected skin lesions caused by infection with fungi or yeasts, when inflammation is not prominent
in primary or secondary infections due to bacteria
in rosacea
in acne vulgaris
in pruritus without inflammation
in the eyes
in patients with markedly impaired circulation, since skin ulceration has occurred
in these patients, following the use of corticosteroids on occluded areas of skin.
Precautions
Manifestations of hypercortisolism (Cushing’s syndrome) and reversible hypothalamic-pituitary-adrenal (HPA) axis suppression can occur in some individuals as a result of
increased systemic absorption of topical corticosteroids.
Avoid contact with the eyes upon topical application.
Childn <3 yrs.
Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Clotrimazole + Hydrocortisone Topical :
Topical: Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis.
Mechanism of Action
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.
Note
Clori HC 1%+1% Cream manufactured by Amulet Pharmaceuticals Ltd.. Its generic name is Clotrimazole + Hydrocortisone Topical. Clori HC is availble in Bangladesh.
Farmaco BD drug index information on Clori HC Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.