Civox E/E Drops
Ciprofloxacin 0.3% E/E prep
300 mg/100 ml
Popular Pharmaceuticals Ltd.
| Pack size | 5 ml bot |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 35.13 AED |
Indications
Civox E/E Drops is used for:
Otitis media, Superficial ophthalmic infections, Otitis externa, Bacterial Conjunctivitis, Corneal Ulcers (Keratitis)
Adult Dose
Bacterial Conjunctivitis
Solution/Eye drop:
1-2 drops instilled into conjunctival sac(s) every two hours with the patient awake on days 1-2, then 1-2 drops every four hours with the patient awake on days 3-7
Eye Ointment:
0.5-in. (1.25-cm) ribbon applied into conjunctival sac every eight hours on days 1-2, then 0.5-in. (1.25-cm) ribbon every twelve hours on days 3-7
Corneal Ulcers (Keratitis)
Solution/Eye drop:
2 drops every 15 minutes for 6 hours, then 2 drops every 30 minutes for the remainder of day 1, then 2 drops every one hour on day 2, and finally 2 drops every four hours on days 3-14
Ointment: Not indicated for keratitis
Child Dose
Bacterial Conjunctivitis
<1 year: Safety and efficacy not established
>1 year (solution): 1-2 drops instilled into conjunctival sac(s) every two hours with the patient awake on days 1-2, then 1-2 drops every four hours with the patient awake on days 3-7
>2 years (ointment): 0.5-in. (1.25-cm) ribbon applied into conjunctival sac every eight hours on days 1-2, then 0.5-in. (1.25-cm) ribbon every twelve hours on days 3-7
Renal Dose
Administration
Contra Indications
Ciprofloxacin is contraindicated in patients who have hypersensitivity to Ciprofloxacin or other quinolones.
Resistance to ciprofloxacin
Precautions
Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, were reported; some reactions were accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal or facial edema, dyspnea, urticaria, and itching
May result in overgrowth of nonsusceptible organisms, including fungi; if superinfection occurs, appropriate therapy should be initiated
Prolonged use of Ciprofloxacin may result in overgrowth of nonsusceptible organisms, including fungi. Ciprofloxacin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction.
Careful monitoring, including slit-lamp microscopy and fluorescein staining when appropriate, may be necessary in some patients receiving ophthalmic ciprofloxacin therapy
Discontinue therapy at the first appearance of a skin rash or any other sign of hypersensitivity reaction
Do not touch the dropper tip to any surface, as this may contaminate the solution
Contact lenses should be removed before administration
Pregnancy-Lactation
Pregnancy category: C
Lactation: The Drug is distributed into milk; use with caution
Interactions
Specific drug interaction studies have not been conducted with ophthalmic ciprofloxacin.
Adverse Effects
Side effects of Ciprofloxacin 0.3% E/E prep :
>10%
Burning,Ciprofloxacin precipitate in superficial portion of corneal defect,Stinging
1-10%
Conjunctival hyperemia,Crystals or scales on eyelashes,Foreign-body sensation,Itching,Keratopathy or keratitis,Lid margin crusting,Unpleasant taste after instillation
<1%
Corneal infiltrates,Corneal staining,Decrease in vision,Lid edema,Ocular discomfort,Photophobia,Sensitivity reactions,Tearing
Mechanism of Action
Ciprofloxacin promotes breakage of double-stranded DNA in susceptible organisms and inhibits DNA gyrase, which is essential in reproduction of bacterial DNA.
Note
Civox 300 mg/100 ml E/E Drops manufactured by Popular Pharmaceuticals Ltd.. Its generic name is Ciprofloxacin 0.3% E/E prep. Civox is availble in Bangladesh.
Farmaco BD drug index information on Civox E/E Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.