Cinaron Tablet
Cinnarizine
15mg
Square Pharmaceuticals PLC.
| Pack size | 200's pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 1.35 AED |
Indications
Cinaron Tablet is used for:
Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders
Adult Dose
Oral
Peripheral vascular disease
Adult: 75 mg bid or tid.
Motion sickness
Adult: 30 mg 2 hr before travel then 15 mg 8 hourly during the journey if necessary.
Cerebrovascular disorders
Adult: 75 mg once daily.
Vestibular disorders
Relief of symptoms of vestibular disorders, such as vertigo, tinnitus, nausea, and vomiting in Meniere’s disease
Adult: 30 mg tid or 75 mg 1-2 times daily.
Child Dose
Oral
Motion sickness
Child: 5-12 yr 15 mg 2 hr before travel then 7.5 mg 8 hrly during the journey as necessary.
Vertigo and vestibular disorders
Child: 5-12 yr 15 mg tid.
Renal Dose
Administration
Should be taken with food.
Contra Indications
Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.
Precautions
Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.
Pregnancy-Lactation
The safety of Cinnarizine in human pregnancy has not been established although studies in animals have not demonstrated teratogenic effects. Therefore, it is not advisable to administer Cinnarizine in pregnancy
Interactions
CNS depressant effect enhanced with alcohol. Action potentiated by domperidone. Increased sedative effect w/ CNS depressants or TCAs.
Adverse Effects
Side effects of Cinnarizine :
Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.
Mechanism of Action
Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity.
Note
Cinaron 15mg Tablet manufactured by Square Pharmaceuticals PLC.. Its generic name is Cinnarizine. Cinaron is availble in Bangladesh.
Farmaco BD drug index information on Cinaron Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.