Cefopar IM/IV Injection

Cefoperazone
2gm
Opsonin Pharma Limited
Pack size 1's Pack
Dispensing mode
Source
Agent
Retail Price 400.00 AED

Indications

Cefopar IM/IV Injection is used for: Respiratory Tract Infections, Peritonitis and Other Intra-abdominal Infections, Bacterial Septicemia, Infections of the Skin and Skin Structures, Pelvic Inflammatory Disease, Endometritis, and Other Infections of the Female Genital Tract, Urinary Tract Infections

Adult Dose

Parenteral Susceptible infections Adult: As sodium: 2-4 g daily in 2 divided doses, increased to 12 g daily in 2-4 divided doses for severe infections given as deep IM or IV infusion.

Child Dose

Renal Dose

Renal impairment: 1-2 g daily.

Administration

Contra Indications

Hypersensitivity to cephalosporin.

Precautions

History of penicillin allergy; renal or hepatic impairment; pregnancy, lactation; cystic fibrosis, clostridium difficile-associated diarrhea, hemorrhage. Prolonged use may result in the overgrowth of nonsusceptible organisms.

Pregnancy-Lactation

Interactions

Disulfiram-like reaction with alcohol. Potentiates anticoagulants. Potentially Fatal: Enhances nephrotoxicity by aminoglycosides and furosemide.

Adverse Effects

Side effects of Cefoperazone : Skin rash, urticaria; eosinophilia, diarrhoea, nausea, vomiting; phloebitis; hypoprothrombinaemia; superinfection. Potentially Fatal: Neuromuscular hypersensitivity; nephrotoxicity.

Mechanism of Action

Cefoperazone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Note

Cefopar 2gm IM/IV Injection manufactured by Opsonin Pharma Limited. Its generic name is Cefoperazone. Cefopar is availble in Bangladesh. Farmaco BD drug index information on Cefopar IM/IV Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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