Cadosil LD Ointment

Calcium Dobesilate 4% + Lidocaine 2% + Dexamethasone Acetate 0.025% rectal prep

4 gm + 25 mg + 2 gm/100 g

UniMed UniHealth Pharmaceuticals Ltd.

Pack size	30g
Dispensing mode
Source
Agent
Retail Price	170.00 AED

Indications

Cadosil LD Ointment is used for: Internal and external hemorrhoids, anal pruritus, anal eczema, anitis, perianitis, acute hemorrhoidal thrombosis and anal fissure. Pre and postoperative treatment in cases of hemorrhoidectomy

Adult Dose

Rectal Ointment Apply 2 -3 times daily. Apply in the morning and bedtime and if possible after defecation. In case of external hemorrhoids or anal pruritus, apply a thin layer of the ointment several times a day. The duration of the treatment is generally of few days.

Child Dose

Renal Dose

In case of renal insufficiency, this oinement should not be used during longer periods. Avoid long-lasting treatments.

Administration

Apply in the morning and bedtime and if possible after defecation. If the ointment is preferred, use the applicator by screwing it to the tube. Insert the applicator as deep as possible in the anus then press the tube gently while withdrawing it.

Contra Indications

Hypersensitivity

Precautions

In case of renal insufficiency, this ointment should not be used during longer periods. Avoid long-lasting treatments.

Pregnancy-Lactation

Pregnancy category C. Studies in pregnant women or animals are not available and in humans, it is not known whether Calcium Dobesilate crosses the placental barrier. On the other hand, after topical administration, Lidocaine Hydrochloride and Dexamethasone Acetate are resorbed in variable quantities and can have systemic effects. Moreover, both substances cross the placental barrier. In these conditions, this rectal ointment should be administered during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lactation: Calcium Dobesilate is excreted in the maternal milk in low amounts but it is not known whether this is the case with local use. After topical administration, Lidocaine Hydrochloride and Dexamethasone Acetate are excreted in the maternal milk. As a precaution, it should be decided between discontinuing the treatment or the breast-feeding.

Interactions

Adverse Effects

Side effects of Calcium Dobesilate 4% + Lidocaine 2% + Dexamethasone Acetate 0.025% rectal prep : Very rare cases have been reported: Modifications of the intestinal transit, temporary burning sensation and local pain. Hypersensitivity reactions together with skin reactions and/or fever can occur. These reactions can be of allergic origin and in this case, the treatment must be discontinued.

Mechanism of Action

Calcium Dobesilate acts on the capillary walls by regulating their impaired physiological functions - i.e. increased permeability and decreased resistance and on different signs of inflammation. It also has an antithrombotic activity. Lidocaine hydrochloride, a local anesthetic, contributes to relieve pain. Dexamethasone Acetate, a Corticosteroid for topical use, possesses anti-inflammatory and antipruritic actions.

Note

Cadosil LD 4 gm + 25 mg + 2 gm/100 g Ointment manufactured by UniMed UniHealth Pharmaceuticals Ltd.. Its generic name is Calcium Dobesilate 4% + Lidocaine 2% + Dexamethasone Acetate 0.025% rectal prep. Cadosil LD is availble in Bangladesh. Farmaco BD drug index information on Cadosil LD Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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