Alphagan P Eye Drops

Brimonidine Tartrate Eye prep
0.15%
Eskayef Pharmaceuticals Ltd.
Pack size 5ml
Dispensing mode
Source
Agent
Retail Price 664.00 AED

Indications

Alphagan P Eye Drops is used for: Open-angle glaucoma, Ocular hypertension

Adult Dose

Ophthalmic Open-angle glaucoma Indicated to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension 0.1%, 0.15%, 0.2% ophthalmic solution Adult: Instill 1 drop of a solution three times daily, approximately 8 hours apart. Ocular Redness Indicated to relieve ocular redness caused by minor eye irritations 0.025% ophthalmic solution Instill 1 drop in the affected eye(s) every 6-8 hours.

Child Dose

<2 years: Contraindicated >2 years: Instill 1 drop of a solution bid-tid.

Renal Dose

Administration

Contra Indications

This eye drops are contraindicated in patients with hypersensitivity to brimonidine tartrate or any component of this medication.This product is also contraindicated in patients receiving monoaminase oxidase inhibitor therapy.

Precautions

General Brimonidine ophthalmic solution should be used with caution in patients with known hypersensitivity to other alpha-adrenoceptor agonists. Although brimonidine had minimal effect on blood pressure and heart rate of patients in clinical studies, caution should be exercised in treating patients with severe cardiovascular disease. Brimonidine has not been studied in patients with hepatic or renal impairment; caution should be exercised in treating such patients. Brimonidine should be used with caution in patients with depression, cerebral or coronary insufficiency. Lactation: It is not known whether this drug is excreted in milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Pregnancy-Lactation

Pregnancy Category: B Lactation: It is not known whether this drug is excreted in milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Interactions

Antihypertensives/cardiac glycosides may lower blood pressure. Use with CNS depressants may result in an additive or potentiating effect. Tricyclic antidepressants may potentially blunt the hypotensive effect of systemic clonidine. Monoamine oxidase inhibitors may result in increased hypotension. Contraindicated (9) isocarboxazid linezolid phenelzine procarbazine rasagiline selegiline selegiline transdermal thalidomide tranylcypromine Serious (19) alfentanil buprenorphine buprenorphine buccal buprenorphine subdermal implant buprenorphine transdermal buprenorphine, long-acting injection codeine fentanyl fentanyl intranasal fentanyl iontophoretic transdermal system fentanyl transdermal fentanyl transmucosal hydrocodone hydromorphone methadone morphine oxycodone oxymorphone remifentanil

Adverse Effects

Side effects of Brimonidine Tartrate Eye prep : Frequency Not Defined Oral dryness Conjunctival hyperemia Allergic conjunctivitis Eye pruritus Rash Photophobia Headache Fatigue Dizziness Dyspepsia Blepharitis Eye discharge

Mechanism of Action

Brimonidine is an alpha 2-adrenoceptor agonist which works to reduce aqueous humor production and increase uveoscleral flow.

Note

Alphagan P 0.15% Eye Drops manufactured by Eskayef Pharmaceuticals Ltd.. Its generic name is Brimonidine Tartrate Eye prep. Alphagan P is availble in Bangladesh. Farmaco BD drug index information on Alphagan P Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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